… Mice and rats synthesize testosterone through the Δ 4 … (PGs) from arachidonic acid (AA). The
main steps of the … kg) inhibited the masculinization of male genitalia in GD18 embryos when …

… acids (HETE) and 15-HETE from arachidonic acid in the testes … reductions in serum
testosterone and epididymal sperm … affects the process of masculinization while the disruption of …

… signaling cascade required for fetal masculinization. … ) is stimulated by testosterone, whereas
external genitalia and … , and DBP reportedly elevate testosterone levels in mice at early …

… in vivo and its metabolites are involved in inflammation and … the synthesis and secretion of
testosterone in animal studies, … effects or associated with key confounders at p < 5 × 10 −8 . …

… However, this apparent lack of effect on masculinization was blunted by the … pathway and
testosterone, a study has been performed with fetal rat testes ex vivo in which arachidonic acid …

… cascade is involved in the conversion of arachidonic acid (AA… sinus and external genitalia,
testosterone is rapidly and … exposure of pregnant rats during the masculinization window (15.5…

… the arachidonic acid cascade can inhibit testosterone synthesis … arachidonic acid cascade
is involved in the masculinizing action of testosterone on embryonic external genitalia in mice. …

… The arachidonic acid cascade is involved in the masculinizing action of testosterone on
embryonic external genitalia in mice. Proc Natl Acad Sci USA 83(12):4346-4349 https://www.ncbi…

… actions being mediated via decreased testicular testosterone production rather than a direct
… implicated the arachidonic acid cascade in the masculinisation of male mouse embryos (…

… COXs are involved in the conversion of arachidonic acid to … In mice, indomethacin has been
shown to inhibit masculine … and mortality, we exposed zebrafish embryos to drugs from 0 to 6 …